Lys’ias (dissolving), a nobleman of the blood-royal, 1 Macc. 3:32; 2 Macc. 11:1, who was entrusted by Antiochus Epiphanes (cir. b.c. 166) with the government of southern Syria and the guardianship of his son Antiochus Eupator. 1 Macc. 3:32; 2 Macc. 10:11. After the death of Antiochus Epiphanes, b.c. 164, Lysia assumed the government as guardian of his son, who was yet a child. 1 Macc. 6:17. In b.c. 164 he, together with his ward, fell into the hands of Demetrius Soter, who put them both to death. 1 Macc. 7:2-4; 2 Macc. 14:2.